ZRÓŻNICOWANIE GATUNKOWE I LEKOWRAŻLIWOŚĆ GRZYBÓW WYOSOBNIONYCH Z KRWI PACJENTÓW SZPITALA UNIWERSYTECKIEGO W BYDGOSZCZY W LATACH 2005-2008
[THE SPECIES VARIETY AND DRUG SUSCEPTIBILITY OF FUNGI ISOLATED FROM BLOOD SAMPLES OF PATIENTS OF THE DR. A. JURASZ UNIVERSITY HOSPITAL IN BYDGOSZCZ IN THE YEARS 2005-2008]

Streszczenie.

Przeprowadzono retrospektywną analizę szczepów grzybów izolowanych z próbek krwi pacjentów Szpitala Uniwersyteckiego w Bydgoszczy w latach 2005-2008. W okresie pierwszych trzech lat objętych analizą obserwowano wzrost liczby izolatów. Łącznie wyosobniono 79 szczepów od 68 chorych, z czego 96,2% stanowiły drożdże rodzaju Candida, pozostałe należały do rodzaju Cryptococcus.

Abstract.

The aim of the study was retrospective analysis of the species variety and the drug susceptibility to antifungal drugs of fungal strains isolated form blood samples of patients of the dr. A. Jurasz University Hospital in Bydgoszcz, in the years 2005-2008. A total of 79 strains patients was isolated from 68 during these four years. Above 96% strains belong to Candida spp., while three strains – to Cryptococcus spp. Almost 56% strains were isolated from more than one blood sample. In the first
three years of analysis gradual increase of the number of cultured strains was observed, but in 2008 the
decrease was noticed. The majority of strains were obtained from patients of the Anesthesiology and
Intensive Care Clinic (32,9%) and the Pediatrics, Hematology and Oncology Clinic (24,1%). Every
year the same species were the most frequently cultered: C. albicans, C. parapsilosis i C. glabrata. C. albicans was found as the dominant species each year. Almost 32% of strains were isolated from blood samples obtained by peripheral insertion of a needle and by catheter as well. C. parapsilosis was the most frequently isolated species from those cases (48,0%). Among non-C. albicans species there were higher percentages of strains resistant to flucytosine, amphotericin B and fluconazole observed.