OCENA ZALEŻNOŚCI MIĘDZY POCHODZENIEM SZCZEPÓW CANDIDA SP., A ICH ZDOLNOŚCIĄ WYTWARZANIA BIOFILMU NA POWIERZCHNI RÓŻNYCH BIOMATERIAŁÓW
[THE EVALUATION OF RELATIONSHIP BETWEEN THE ORIGIN OF CANDIDA SP. AND THE ABILITY OF BIOFILM FORMATION ON SURFACE OF DIFFERENT BIOMATERIALS]

Streszczenie.

Badania prowadzono na 150 szczepach Candida sp. izolowanych od pacjentów 14 Klinik / Oddziałów. Zdolność wytwarzania biofilmu oceniano metodą redukcji TTC wobec 5 biomateriałów: lateksu silikonowanego, polichlorku winylu, polistyrenu, nylonu oraz polimetakrylanu metylu. Stwierdzono związek między pochodzeniem szczepów a zdolnością wytwarzania biofilmu.

Abstract.

The increase of fungal infections in recent years is connected with the progress in medicine. The vast usage of biomaterials is an inseparable element of contemporary medicine but it also leads to development of infections. The ability to produce biofilm by those yeasts plays an important role in the pathogenesis of candidiasis. Candida biofilm can form on the surface of plastic materials (silicon, polychloride vinyl, polymethacrylate methyl) used to catheters, drains and dentures production that
is why it is a serious problem in case of fungal infections in patients who during the diagnosis and treatment have contact with biomaterials. The aim of the study was the assessment of ability to form biofilm on the surface of different biomaterials (latex silicon, polychloride vinyl, polystyrene, nylon and polymethacrylate methyl). 150 strains of Candida sp. were examined: 85 (56,7%) C. albicans and 65 (43,3%) C. non-albicans. The examined yeasts produced biofilm on the surface of polymethacrylate methyl in 39,3%, latex silicone in 38,7%, polychloride vinyl in 38,0%, polystyrene in 35,3% and nylon in 30,7%. Biofilm was most frequently produced by the strains of C. albicans, C. tropicalis, C. glabrata, C. parapsilosis, C. krusei and C. lusitaniae species.