Wrażliwość na fluorochinolony pałeczek Klebsiella pneumoniae izolowanych z moczu
[Susceptibility of Klebsiella pneumoniae isolated from urinary tract infections to quinolones]

Streszczenie

Badano wrażliwość na fluorochinolony 60 szczepów Klebsiella pneumoniae. Oznaczono wartość MIC dla norfloksacyny, ciprofloksacyny i gatifloksacyny. Wśród badanych szczepów 52 (86,7%) były wrażliwe na gatifloksacynę, 46 (76,7%) na norfloksacynę i 31 (51,7%) na ciprofloksacynę.

Abstract

Urinary Tract Infections (UTIs) are the most prevalent infections worldwide both in males and females. K. pneumoniae is one of the major pathogens causing UTIs. Fluoroquinolones are effective drugs for treating infections caused by Klebsiella spp. The aim of this study was to evaluated the susceptibility to three fluoroquinolones of K. pneumoniae strains isolated from urine. The MICs of ciprofloxacin was determined by agar dilution method and the MICs of norfloxacin and gatifloxacin by E-test. Among analysed K. pneumoniae strains 86,7% was susceptible to gatifloxacine, 76,7% to
norfloxacin and 51,2% to ciprofloxacine.