NARASTANIE STOPNIA KOLONIZACJI KOBIET W CIĄŻY I NOWORODKÓW PRZEZ STREPTOCOCCUS AGALACTIAE NA OBSZARZE POLSKI POŁUDNIOWO-WSCHODNIEJ
[INCREASING STREPTOCOCUS AGALACTIAE COLONIZATION OF PREGNANT WOMEN AND NEWBORNS IN SOUTH-EASTERN REGION OF POLAND]

Streszczenie

Streptococcus agalactiae (GBS) może być przyczyną poważnych powikłań w czasie ciąży oraz zakażeń noworodków o różnym nasileniu. Na podstawie uzyskanych wyników wykazano, iż kobiety ciężarne zaliczone do grupy wysokiego ryzyka osiągnęły kolonizacje GBS na poziomie 20%, zaś kobiety z ciążą prawidłową 17,2%. Częstość kolonizacji noworodków z ciąży wysokiego ryzyka wynosiła 35%, zaś z ciąży prawidłowych 26,7%. Ponadto, wykazano podwyższoną częstość wykrywania szczepów GBS z mechanizmem oporności typu MLSB u kobiet z ciążą wysokiego ryzyka oraz u ich dzieci.

Abstract.

Streptococcus agalactiae, group B streptococci (GBS) are a constituent of normal vaginal bacterial microflora which often do not give any clinical symptoms. On the other hand, during pregnancy there are optimal conditions for GBS multiplication in the vagina, which may have very serious consequences for both the mother and her child. The women (n = 563) that participated in our study were in their 3rd trimester and they were divided into groups: normal pregnancy or high risk pregnancy. We also
examined their newborns. GBS identification was done basing on traditional culture method and its
modification recommended by the CDC. We showed a slightly improved (about 4%) effectiveness of
GBS detection in pregnant women using the CDC method. In high risk pregnancy GBS colonization was 20% (among them 35% newborns were colonized) and in normal pregnancy it was found to be 17.2% (among them 26.7% newborns were colonized). Both in the high risk group and their newborns we confirmed a higher and statistically significant frequency of detection of GBS strains which had MLSB mechanism of antibiotic resistance. In newborns we confirmed two cases which were fatal. The
results of our study show the need and necessity for implementing unified procedures recommended
by the CDC in Poland.